Search on: PHOSPHOENOLPYRUVATE HEXOSE PHOSPHOTRANSFERASES 
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Descriptor English:   Phosphoenolpyruvate Sugar Phosphotransferase System 
Descriptor Spanish:   Sistema de Fosfotransferasa de Azúcar del Fosfoenolpiruvato 
Descriptor Portuguese:   Sistema Fosfotransferase de Açúcar do Fosfoenolpiruvato 
Synonyms English:   Hexose Phosphotransferases, Phosphoenolpyruvate
Phosphoenolpyruvate Glycose Phosphotransferase System
Phosphoenolpyruvate Hexose Phosphotransferases
Phosphoenolpyruvate-Glycose Phosphotransferase System
Phosphotransferase System, Phosphoenolpyruvate-Glycose
Phosphotransferases, Phosphoenolpyruvate Hexose
System, Phosphoenolpyruvate-Glycose Phosphotransferase  
Tree Number:   D05.500.562.484
D08.811.600.700
D08.811.913.696.620.650
Definition English:   The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to its sugar substrates (the PTS sugars) concomitant with the translocation of these sugars across the bacterial membrane. The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. The PTS has also been implicated in the induction of synthesis of some catabolic enzyme systems required for the utilization of sugars that are not substrates of the PTS as well as the regulation of the activity of ADENYLYL CYCLASES. EC 2.7.1.-. 
History Note English:   80 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   21047 
Unique Identifier:   D010731 

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